Approved: New Cancer Drugs

FDA approves three new cancer medications

(RxWiki News) The US Food and Drug Administration (FDA) has approved three new cancer medications.

First, the FDA approved Tabrecta (capmatinib) to treat adults with a certain type of lung cancer. This medication is approved to treat advanced non-small cell lung cancer (NSCLC) in those with tumors that have a certain type of mutation.

This medication is available in tablet form and is to be taken twice a day with or without food.

Common side effects of Tabrecta may include nausea, vomiting, feeling tired, shortness of breath, reduced appetite, and swelling of your lower legs and hands.

The approval of this medication was granted to Novartis.

The second approval is for Qinlock (ripretinib).

This medication is approved for adults with a type of gastrointestinal tumor: advanced gastrointestinal stromal tumor (GIST). It's meant for those who have already tried three or more treatments (kinase inhibitors including imatinib). It is available in tablets and is to be taken once daily with or without food.

Common side effects of Qinlock include hair loss, feeling tired, nausea, vomiting, stomach pain, diarrhea/constipation, muscle pain and reduced appetite. It can also cause a skin reaction in the palms and soles.

The FDA granted approval to Deciphera Pharmaceuticals, Inc.

The third approval is for Retevmo (selpercatinib).

This new medication is approved to treat the following (when specific genetic mutations are present):

  • NSCLC in adults
  • Two types of thyroid cancer in children (12 years old and older) and adults

This medication is available in capsules. The dose is based on weight and is to be given twice a day.

Common side effects of Retevmo include dry mouth, diarrhea, feeling tired, swelling of your arms, legs, hands, and feet, rash, constipation, changes in blood cell counts and platelets and changes in labs (calcium, salt, cholesterol, sugar levels and liver enzymes).

The FDA granted approval to Eli Lilly and Company.

These three medications can harm your unborn baby, so they can't be taken during pregnancy.

Also, these medications can interact with several other medications. Your doctor will adjust your medications or the dose if necessary.

Speak with your health care provider if you have any questions.