Vyepti is used to prevent migraine headaches.

Vyepti Overview

Reviewed: October 18, 2021

Vyepti is a prescription medication used to prevent migraine headaches in adults. 

This medication belongs to a group of drugs called humanized monoclonal antibodies. It works by blocking calcitonin gene-related peptide, or CGRP, a substance in your brain that is thought to play a role in triggering migraine.

Vyepti is given directly into a vein (IV) every 3 months. The infusion lasts 30 minutes.

Common side effects include stuffy nose, scratchy throat and allergic reactions.

How was your experience with ?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking ?

What are you taking for?

Choose one
  • Other

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend to a friend?

Vyepti Cautionary Labels


Uses of Vyepti

Vyepti is a prescription medicine used for the preventive treatment of migraine in adults. 

It is not known if Vyepti is safe and effective in children.



For more information on this medication choose from the list of selections below.

Vyepti Drug Class

Vyepti is part of the drug class:

Side Effects of Vyepti

Vyepti may cause serious side effects. See the "Vyepti Precautions" section.

Common side effects include:

  • stuffy nose and scratchy throat
  • allergic reactions

This is not a complete list of side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Vyepti Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Vyepti Precautions

Vyepti may cause serious side effects, including:

Allergic reactions. Allergic reactions can happen after receiving Vyepti. Call your healthcare provider or get emergency medical help right away if you have any of the following symptoms of an allergic reaction:

  • rash
  • swelling of your face, lips, tongue or throat
  • trouble breathing
  • hives
  • redness in your face

Do not receive Vyepti if you are allergic to eptinezumab-jjmr or any of the ingredients in Vyepti.

Vyepti Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Vyepti, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before you receive Vyepti, tell your healthcare provider about all of your medical conditions, including if you:

  • are pregnant 
  • are breastfeeding or plan to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Vyepti and Pregnancy

Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if Vyepti will harm your unborn baby.

Vyepti and Lactation

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if Vyepti passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while using Vyepti.

Vyepti Usage

  • Vyepti will be given by a healthcare provider in a healthcare setting.
  • Vyepti is given by intravenous (IV) infusion in your vein.
  • Vyepti will be given over 30 minutes every 3 months.

If you have questions about your infusion schedule, ask your healthcare provider.

Vyepti Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

The recommended Vyepti dosage is 100 mg administered by intravenous infusion every 3 months. Your healthcare provider may increase your dosage to 300 mg administered by intravenous infusion every 3 months.

Vyepti Overdose

Vyepti is administered by a healthcare provider in a medical setting. It is unlikely that an overdose will occur. However, if an overdose is suspected, seek emergency medical attention.


All RxWiki content including health news, medication pages, and condition pages published prior to February 2023, was written and maintained by on-staff pharmacists. Please be advised that this content is no longer actively maintained and may now contain outdated information. If you have any questions regarding previously published content, please contact support@rxwiki.com.