Alli

Alli helps you lose weight. May cause gas and even a oily discharge. Eating foods high in fat can make these side effects worse. Read all food labels and avoid foods that have more than 30% fat.

Alli Overview

Updated: 

Alli is an over the counter medication for weight loss. Alli belongs to a group of drugs called lipase inhibitors, which work by preventing the absorption of fat in your body. 

This medication comes in capsule form and is taken up to 3 times daily with each fat-containing meal. 
 
Common side effects include oily spotting, stomach pain, and gas with oil or stool discharge.

How was your experience with Alli?

First, a little about yourself

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What tips would you provide a friend before taking Alli?

What are you taking Alli for?

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  • Other
  • Obesity

How long have you been taking it?

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  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Alli work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend Alli to a friend?

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Alli Cautionary Labels

precautionsprecautions

Uses of Alli

Alli is a medicine used to help obese people lose weight and keep this weight off. Alli should be used together with a reduced-calorie diet that your doctor will recommend.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. 
 

Alli Drug Class

Alli is part of the drug class:

Side Effects of Alli

Because Alli works by blocking the absorption of dietary fat, it is likely that you will experience some changes in bowel habits. These generally occur during the first weeks of treatment; however, they may continue throughout your use of Alli.
These changes may include

  • oily spotting
  • gas with discharge
  • urgent need to go to the bathroom
  • oily or fatty stools 
  • an oily discharge
  • increased number of bowel movements
  • an inability to control bowel movements 
  • Due to the presence of undigested fat, the oil seen in a bowel movement may be clear or have a coloration such as orange or brown.

These bowel changes are a natural effect of blocking the fat from being absorbed and indicate that Alli is working. They generally occur early in treatment, particularly after meals containing higher amounts of fat than are recommended. These symptoms are often temporary and may lessen or disappear as you continue treatment and keep to your recommended diet of meals containing no more than about 30% fat. However, these side effects may occur in some individuals over a period of 6 months or longer.

  • In obese adolescent patients treated with Alli, the side effects reported were similar to those observed in adults.
  • If you are concerned about these or any other side effects you experience while taking Alli, talk to your doctor or pharmacist.

Alli Interactions

Be sure to discuss with your doctor all medications (including herbal products) you are currently taking, including medicines you can get without a prescription (over-the-counter), to determine if Alli can be taken in addition to these medications.

  • If you are taking cyclosporine, Alli and cyclosporine should be taken at least 2 hours apart.
  • If your cyclosporine levels are being measured, more frequent monitoring may be necessary. 
  • If you are taking levothyroxine, orlistat and levothyroxine should be taken at least 4 hours apart.

Alli Precautions

You should not use Alli if you:

  • consistently have problems absorbing food (chronic malabsorption); or
  • have gallbladder problems; or
  • are pregnant or are breastfeeding a child; or
  • have ever had an allergic reaction to Alli or any of the inactive ingredients in Alli

Alli has been shown to reduce the absorption of certain vitamins. You should take a multivitamin containing vitamins D, E, K, and beta-carotene once a day at least 2 hours before or after the administration of Alli, such as at bedtime.

Some patients taking Alli may develop an increased risk for the development of kidney stones. Promptly report any symptoms of back pain or blood in the urine.

Some patients prescribed Alli may already be at increased risk for the formation of gall stones. Weight loss with Alli can increase the risk of gall stones. Promptly report any symptoms of pain in the upper right portion of the abdomen. The pain may be accompanied by nausea and vomiting.

There have been rare reports of severe liver injury in patients taking Alli. Promptly discontinue Alli and contact your healthcare provider if you develop symptoms suggestive of liver impairment, such as loss of appetite, itching, yellowing of the skin, dark urine, light colored stools, or right upper quadrant pain.

Alli Food Interactions

You should use Alli together with a nutritionally balanced, mildly reduced-calorie diet that contains no more than about 30% of calories from fat.

Read all food labels and avoid foods that have more than 30% fat.

Inform MD

Before beginning treatment with Alli, make sure your doctor knows if you are:

  • allergic to any medicines, foods, or dyes
  • taking any other weight-loss medication
  • taking cyclosporine
  • taking thyroid medicine
  • taking any other medicines (including those not prescribed by your doctor)
  • taking any dietary supplements, including herbal products
  • planning to become pregnant
  • anorexic or bulimic

This information will help you and your physician decide if the expected advantages of Alli are greater than any possible disadvantages.

Alli and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. Alli should not be used during pregnancy as it may harm your unborn baby.

Weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. A minimum weight gain, and no weight loss, is currently recommended for all pregnant women, including those who are already overweight or obese, due to the obligatory weight gain that occurs in maternal tissues during pregnancy. 

Alli and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Alli is excreted in human breast milk or if it will harm your nursing baby.

Alli Usage

  • Alli comes as a capsule to be taken with liquid at each main meal that contains fat.
  • You can take Alli in conjunction with a mildly reduced-calorie diet up to 3 times a day.
  • Each time you take Alli, your meal should contain no more than about 30% of calories from fat. 
  • Take Alli during meals or up to one hour after a meal. If you occasionally miss a meal or have a meal without fat, you can omit your dose of Alli. 
  • You should use Alli together with a nutritionally balanced, mildly reduced-calorie diet that contains no more than about 30% of calories from fat. 
  • You should evenly divide your daily intake of fat, carbohydrates, and protein over 3 main meals.
  • You should try to follow a healthy eating plan such as the one developed by the American Heart Association. 
  • Following this eating plan will help you lose weight while decreasing some of the possible gastrointestinal effects you may experience while taking Alli.

Alli Dosage

Take Alli exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The recommended dose is one 60 mg capsule by mouth with liquid at each main meal that contains fat. You can take Alli in conjunction with a mildly reduced-calorie diet up to 3 times a day.

Alli Overdose

If you take too much Alli, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

  • Store at 20 - 25°C (68 - 77°F).
  • Keep this and all medicines out of the reach of children.
  • Protect drug from excessive light, humidity and temperatures over 30°C (86°F).