Bone Rx Boosted Breast Cancer Survival
Nearly all postmenopausal women with early-stage HR+ breast cancer are treated with aromatase inhibitors. But these drugs can significantly compromise bone health and up the risk of fractures.
Giant Step Forward for Giant-Cell Tumor of the Bone
Denosumab – sold under the brand names of Prolia for the treatment of osteoporosis and Xgeva for fracture prevention in patients with metastatic cancers to the bone – may be effective in treating people with a condition known as giant-cell tumor of the bone.
Which Bone Metastasis Drug Is Better?
When breast cancer spreads to the bones, various drugs are available to control the disease. This class of drugs is called biophosphonates . A manufacturer-funded study suggests its drug is better than others.
FDA Approves Prolia for osteoporosis
On September 16, 2011, the U.S. Food and Drug Administration granted approval for denosumab ( Prolia , Amgen Inc.) as a treatment to increase bone mass in patients at high risk for fracture receiving androgen deprivation therapy (ADT) for nonmetastatic prostate cancer or adjuvant aromatase inhibitor (AI) therapy for breast cancer. In men with nonmetastatic prostate cancer, denosumab also reduced the incidence of vertebral fracture.