Atezolizumab treats a common type of bladder cancer and lung cancer. It works by helping your body’s immune system to fight cancer cells. May cause you to feel tired.

Atezolizumab Overview

Reviewed: May 23, 2016

Atezolizumab is a prescription medication used to treat urothelial carcinoma, the most common type of bladder cancer. Atezolizumab is also approved to treat non-small cell lung cancer (NSCLC).

Atezolizumab belongs to a group of drugs called PD-1/PD-L1 inhibitors. They work to help the body’s immune system fight cancer cells.

This medication is available as an injection and is injected into a vein by a healthcare professional. It is typically administered every 3 weeks. 

Common side effects of atezolizumab include feeling tired, decreased appetite, and nausea. 

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Atezolizumab Cautionary Labels


Uses of Atezolizumab

Atezolizumab is a prescription medication used to treat urothelial carcinoma, a type of bladder and urinary tract cancer. This medication may be given to those:

  • whose cancer has spread or cannot be removed by surgery (advanced urothelial carcinoma), and
  • who are not able to take chemotherapy that contains a medicine called cisplatin, or
  • who have tried chemotherapy that contains platinum, and it did not work or is no longer working

Atezolizumab may be given to those who cannot receive chemotherapy that contains platinum as well as for those whose cancer has spread after chemotherapy that contains platinum as well as those whose cancer has spread within 12 months of receiving chemotherapy before surgery or after surgery.

Atezolizumab is also approved to treat non-small cell lung cancer (NSCLC) that has spread to other parts of the body and has progressed during or after receiving chemotherapy containing platinum. For those with a tumor that has an abnormal EGFR or ALK gene, atezolizumab can be given if an FDA-approved therapy for tumors with these abnormal genes has been tried and it did not work or is no longer working

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information

Atezolizumab Brand Names

Atezolizumab may be found in some form under the following brand names:

Atezolizumab Drug Class

Atezolizumab is part of the drug class:

Side Effects of Atezolizumab

Serious side effects have been reported with atezolizumab. See the “Drug Precautions” section.

Common side effects of atezolizumab include the following:

  • feeling tired
  • decreased appetite
  • nausea
  • urinary tract infection
  • fever
  • constipation

This is not a complete list of side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


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