Cholic Acid

Cholic acid is used to treat rare bile acid synthesis disorders.

Cholic Acid Overview

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Cholic acid is a prescription medication used to treat rare bile acid synthesis disorders due to single enzyme defects and for patients with peroxisomal disorders (including Zellweger spectrum disorders).

Cholic acid comes in capsule form and is usually taken once or twice daily with food. Do not chew, divide, or break cholic acid capsules. Swallow capsules whole.

Common side effects of cholic acid include diarrhea, feeling tired, yellowing of the skin, skin lesions, nausea, vomiting, abdominal pain, and urinary tract infections.

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Cholic Acid Cautionary Labels

precautionsprecautions

Uses of Cholic Acid

Cholic acid is a prescription medication used to treat pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for patients with peroxisomal disorders.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Cholic Acid Brand Names

Cholic Acid may be found in some form under the following brand names:

Cholic Acid Drug Class

Cholic Acid is part of the drug class:

Side Effects of Cholic Acid

Serious side effects have been reported with cholic acid. See the “Cholic Acid Precautions” section.

Common side effects of cholic acid inlcude:

  • diarrhea
  • feeling tired
  • yellowing of the skin
  • skin lesions
  • nausea
  • vomiting
  • abdominal pain
  • urinary tract infections

This is not a complete list of cholic acid side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Cholic Acid Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

This is not a complete list of cholic acid drug interactions. Ask your doctor or pharmacist for more information.

Cholic Acid Precautions

Serious side effects have been reported with cholic acid including the following:

  • Liver impairment. Monitor liver function while taking cholic acid.

Do not take cholic acid if you:

  • are allergic to cholic acid or to any of its ingredients

Cholic Acid Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of cholic acid, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking cholic acid, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to cholic acid or to any of its ingredients
  • have liver problems
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Cholic Acid and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-controlled studies that have been done in pregnant women or animals. Cholic acid should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

There is a pregnancy surveillance program that monitors pregnancy outcomes in women exposed to cholic acid during pregnancy and women who become pregnant during cholic acid treatment are encouraged to enroll. Contact your healthcare provider for more informaiton.

Cholic Acid and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if cholic acid crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using cholic acid.

Cholic Acid Usage

Take cholic acid exactly as prescribed.

Cholic acid comes in capsule form and is usually taken once or twice daily with food. Do not chew, divide, or break cholic acid capsules. Swallow capsules whole.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take 2 doses of cholic acid at the same time.

Cholic Acid Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your age

The recommended dosage for cholic acid is 10-15 mg/kg, divided into 1 or 2 doses daily. Doses should be adjusted on patient response to treatment and the presence of side effects.

Cholic Acid Overdose

If you take too much cholic acid, call your healthcare provider or local Poison Control Center or seek emergency medical attention right away.

If cholic acid is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store cholic acid at room temperature between 15°C and 30°C (59°F and 86°F).
  • Keep this and all medications out of the reach of children.