Detrol

Detrol is a prescription medication used to treat the symptoms of an overactive bladder in adults. Detrol belongs to a group of drugs called antimuscarinic medications, which help the bladder muscles to relax.

This medication comes in an immediate-release tablet form and is usually taken twice a day with or without food.

Common side effects of Detrol include dry mouth, dizziness, and headache.

Detrol is a prescription medicine for adults used to treat the following symptoms due to a condition called overactive bladder:

• urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
• urgency: a strong need to urinate right away
• frequency: urinating often

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Pharmacia and Upjohn Company

The most common side effects with Detrol are:

• dry mouth
• dizziness
• headache
• stomach pain
• constipation

This is not a complete list of side effects of Detrol. Talk to your doctor about any side effect that is bothersome or does not go away.

Tell your doctor about all the medicines you take or are planning to take includine prescription and non-prescription medicines, vitamins, and herbal supplements. If you take Detrol with other medicines, the effects of either could be increased, decreased, or altered. Especially tell your doctor if you take:

• clarithromycin
• cyclosporin
• erythromycin
• itraconazole
• ketoconazole
• miconazole
• vinblastine

This is not a complete list of Detrol drug interactions. Ask your doctor or pharmacist for more information.

Do not take Detrol if you

• are not able to empty your bladder (urinary retention)
• have delayed or slow emptying of your stomach (gastric retention)
• have an eye problem called "uncontrolled narrow-angle glaucoma"
• are allergic to Detrol or to any of its ingredients
• are allergic to Toviaz, which contains fesoterodine

Medicines like Detrol can cause blurred vision or drowsiness. Use caution while driving or doing other dangerous activities until you know how Detrol affects you.

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Detrol there are no specific foods that you must exclude from your diet when receiving Detrol.

Before starting Detrol, tell your doctor about all of your medical and other conditions that may affect the use of Detrol, including

• stomach or intestinal problems or problems with constipation
• problems emptying your bladder or if you have a weak urine stream
• treatment for an eye problem called narrow-angle glaucoma
• liver problems
• kidney problems
• a condition called myasthenia gravis
• if you or any family members have a rare heart condition called QT prolongation (long QT syndrome)
• if you are pregnant or trying to become pregnant. It is not known if Detrol could harm your unborn baby.
• if you are breastfeeding. It is not known if Detrol passes into your breast milk or if it can harm your baby. Talk to your doctor about the best way to feed your baby if you take Detrol.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements. Other medicines can affect how your body handles Detrol.

Your doctor may use a lower dose of Detrol if you are taking:

• Certain medicines for fungus or yeast infections
• Certain medicines for bacterial infections
• Sandimmune (cyclosporine) or Velban (vinblastine)

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Tell your doctor if you are breastfeeding or if you are planning to breastfeed. It is not known if Detrol is excreted in human breast milk or if it will harm your nursing baby.

Take Detrol exactly as your doctor tells you to take it. Your doctor will tell you how many Detrol tablets to take and when to take them.

• Do not change your dose unless told to do so by your doctor.
• You can take Detrol with or without food.
• Take Detrol at the same times each day.
• If you miss a dose of Detrol, just take your next regular dose at your next regular time. Do not try to make up for your missed dose.
• If you take too much Detrol, call your doctor, or go to the hospital emergency room right away.

Medicines like Detrol can cause blurred vision or drowsiness. Use caution while driving or doing other dangerous activities until you know how Detrol affects you.

Take Detrol exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The initial recommended dose of Detrol is 2 mg twice daily. The dose may be lowered to 1 mg twice daily based on how you respond to and tolerate Detrol.

Dosage Adjustment in Specific Populations

For patients with reduced liver or kidney function or who are currently taking certain drugs that can affect how Detrol works in the body, the recommended dose of Detrol is 1 mg twice daily.

If you take too much Detrol, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If Detrol is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

• Store Detrol at 25°C (77°F).
• Keep it in a dry place.
• Keep Detrol and all medicines out of the reach of children.