Farxiga treats type 2 diabetes. Farxiga can cause yeast infections and urinary tract infections.

Farxiga Overview

Reviewed: January 30, 2014

Farxiga is a prescription medication used to control blood sugar levels in people with type 2 diabetes. Farxiga is part of a new class of drugs that work in the kidney to block a protein called SGLT2. By blocking this protein, the drug can remove excess glucose (sugar) through the urine, which helps lower blood sugar levels.

This medication comes in tablet form and is usually taken once daily. Farxiga tablets should be swallowed whole and can be taken with or without food.

Common side effects of Farxiga include low blood sugar (hypoglycemia), yeast infections of the penis or vagina, and backache.

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Farxiga Cautionary Labels


Uses of Farxiga

Farxiga is a prescription medication used to treat type 2 diabetes in adult patients (18 years of age and older).

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Side Effects of Farxiga

Farxiga can cause serious side effects. See "Farxiga Precautions" section.
Contact your doctor as soon as possible if you have any of the following side effects:
  • low blood sugar levels (hypoglycemia) when taking this medicine with a sulfonylurea or insulin. Signs of low blood sugar:
    • shaking, sweating, feeling very anxious, fast heart beat
    • feeling hungry, headache, change in vision
    • a change in your mood or feeling confused.
Common side effects include:
  • yeast infection (thrush) of your penis or vagina
  • back pain
  • passing more water (urine) than usual or needing to pass water more often
  • changes in the amount of cholesterol or fats in your blood (shown in tests)
  • changes in the amount of red blood cells in your blood (shown in tests)

Uncommon side effects (may affect up to 1 in 100 people)

  • unusual vaginal bleeding, discharge, itching or odor
  • thirst
  • constipation
  • excess sweating
  • awakening from sleep at night to pass urine
  • changes in laboratory blood tests (for example creatinine or urea)

This is not a complete list of Farxiga side effects. Ask your doctor or pharmacist for more information.

Farxiga Interactions

Tell your doctor about all of the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor:

  • if you are taking a medicine used to remove water from the body (a diuretic or "water pill")
  • if you are taking other medicines that lower the amount of sugar in your blood such as insulin or a “sulfonylurea” medication
  • valsartan (Diovan, Exforge, Valturna)
  • rifampin (Rifadin, Rimactane)
  • mefenamic acid (Ponstel)

​This is not a complete list of Farxiga drug interactions. Ask your doctor or pharmacist for more information.

Farxiga Precautions

Serious side effects have been reported with Farxiga including the following:

  • loss of too much fluid from your body (dehydration). Signs of dehydration include:
    • extreme thirst
    • feeling very sleepy or tired
    • passing little or no water (urine)
    • fast heart beat
  • urinary tract infection. Signs of a severe infection of the urinary tract include:
    • fever and/or chills
    • burning sensation when passing water (urinating)
    • pain in your back or side

Yeast infection of the penis (balanitis). Men who take Farxiga may get a yeast infection of the skin around the penis. Certain men who are not circumcised may have swelling of the penis that makes it difficult to pull back the skin around the tip of the penis. Other symptoms of yeast infection of the penis include:

  • redness, itching, or swelling of the penis
  • rash of the penis
  • foul smelling discharge from the penis
  • pain in the skin around the penis
  • Talk to your healthcare provider about what to do if you get symptoms of a yeast infection of the vagina or penis. Your healthcare provider may suggest you use an over-the-counter antifungal medicine. Talk to your healthcare provider right away if you use an over-the-counter antifungal medication and your symptoms do not go away.

Bladder cancer. In studies of Farxiga in people with diabetes, bladder cancer occurred in a few more people who were taking Farxiga than in people who were taking other diabetes medications. There were too few cases to know if bladder cancer was related to Farxiga. You should not take Farxiga if you have bladder cancer. Tell your healthcare provider right away if you have any of the following symptoms:

  • blood or a red color in your urine
  • pain while you urinate

Do not take Farxiga if you:

  • are allergic to Farxiga or any of the ingredients in Farxiga. Symptoms of a serious allergic reaction to Farxiga may include:
    • skin rash
    • raised red patches on your skin (hives)
    • swelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing

If you have any of these symptoms, stop taking Farxiga and contact your healthcare provider or go to the nearest hospital emergency room right away.

  • have severe kidney problems or are on dialysis

Farxiga Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Farxiga, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Farxiga tell your doctor about all of your medical conditions including if you:

  • have type 1 diabetes
  • have increased levels of “ketone bodies” in your urine or blood, seen in tests
  • have a kidney problem 
  • have a liver problem
  • have a history of serious heart disease or if you have had a stroke
  • are are on medicines to lower your blood pressure (anti-hypertensives) and have a history of low blood pressure (hypotension) 
  • have very high levels of glucose in your blood which may make you dehydrated
  • have or develop nausea (feeling sick), vomiting or fever or if you are not able to eat or drink. These conditions can cause dehydration.
  • often get infections of the urinary tract
  • are 75 years old or older
  • are taking another medicine for diabetes that contains “pioglitazone”
  • have an increase in the amount of red blood cells in your blood, seen in tests
  • are pregnant or breastfeeding

Tell your doctor about all of the medicines you take including prescription and non-prescription medicines, vitamins and herbal supplements.

Farxiga and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Farxiga and Lactation

Talk to your doctor if you are breastfeeding or plan to breastfeed. Do not use Farxiga if you are breastfeeding. It is not known if this medicine passes into human breast milk.

Farxiga Usage

Take Farxiga exactly as your healthcare provider tells you to take it.

Farxiga comes in tablet form and is taken once daily by mouth with or without food.

Do not change your dose of Farxiga without talking to your healthcare provider.

When your body is under some types of stress, such as fever, trauma (such as a car accident), infection, or surgery, the amount of diabetes medicine you need may change. Tell your healthcare provider right away if you have any of these conditions and follow your healthcare provider’s instructions.

Stay on your prescribed diet and exercise program while taking Farxiga.

Your healthcare provider may do certain blood tests before you start Farxiga and during your treatment.

Your healthcare provider will check your diabetes with regular blood tests, including your blood sugar levels and your A1c.

Follow your healthcare provider’s instructions for treating low blood sugar (hypoglycemia). Talk to your healthcare provider if low blood sugar is a problem for you.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take 2 doses of Farxiga at the same time.

Farxiga Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age
  • your gender

The recommended dose is one 10 mg tablet each day. Your doctor may start you on a 5 mg dose if you have a liver problem.

Farxiga Overdose

If you take too much Farxiga call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Keep this and all medications out of the reach of children.