Omlonti is an eye drop that lowers pressure in the eye in people with open-angle glaucoma or a history of high eye pressure. May change your eye color to brown or a deeper shade of brown.
Omlonti belongs to a group of drugs called prostaglandin E2 receptor agonists. The exact way Omlonti works is unknown, but it is thought to work by acting on the prostaglandin E2 receptor to help fluid drain from the eye, which may lower pressure in the eye.
Omlonti comes as an eye drop. It is usually given as one drop in the affected eye (or both, if both eyes are affected) once daily in the evening.
Common side effects include eye redness and sensitivity to light. Omlonti can cause blurry vision. Do not drive or operate heavy machinery until you know how this medication affects you.
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Uses of Omlonti
Side Effects of Omlonti
Serious side effects may occur with Omlonti. See the "Omlonti Precautions" section.
Common side effects include:
- eye redness
- sensitivity to light
- dry eye
- eye pain after instilling drops
- eye inflammation
- blurry vision
- eye irritation
- changes in vision
This is not a complete list of Omlonti side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or does not go away.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
No drug interactions have been reported by the manufacturer but it is still important to let your doctor know about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.
Serious side effects may occur with Omlonti including the following:
- Pigmentation changes. Omlonti may change your eye color to brown or a deeper shade of brown. This color change usually occurs slowly, but it may be permanent.
- Eyelash changes. Omlonti may cause darkening of the eyelid and skin around your eyes and an increase in the length, thickness, color, or number of your eyelashes or fine hair on your eyelids. The eyelash changes and any darkening of the skin around the eyes usually goes away when you stop using the eye drops.
- Ocular inflammation. Eye swelling has occurred in people taking this medication. Omlonti should be used with caution if you have active ocular inflammation (swelling of the eye), including iritis/uveitis.
- Macular edema. Swelling in part of the retina (back of the eye) has been reported in some patients using Omlonti. This medication should be used with caution in people with macular edema.
Do not take Omlonti if you are allergic to any of its ingredients.
Omlonti Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Omlonti, there are no specific foods that you must exclude from your diet when receiving this medication.
Before taking Omlonti, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to any of its ingredients
- have had cataract surgery or if you have or ever had macular edema (swelling of the back of the eye) or other inflammation of the eye, including iritis (uveitis; swelling and irritation inside the eye)
- have an eye injury or eye infection.
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Omlonti and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medication will harm your unborn baby.
Call your doctor if you become pregnant while using Omlonti eye drops.
Omlonti and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
It is not known if Omlonti crosses into human milk. Because many medications can cross into human milk and because the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Omlonti.
Read the instructions that come with your prescription for detailed information on how to instill the eye drops.
Instill Omlonti eye drops once a day in the evening.
Avoid touching the tip of the bottle to the eye or any surface, as this may injure your eye or contaminate the solution.
The product should be refrigerated before opening, and once it is opened, it can be stored at room temperature for up to 31 days.
If Omlonti is used with other topical eye medications, allow at least 5 minutes between each medication to allow each medication to be fully absorbed.
Remove contact lenses before instilling Omlonti eye drops and wait at least 15 minutes before reinserting contact lenses.
Take this medication exactly as prescibed by your doctor. Follow the directions on your prescription label carefully.
The recommended Omlonti dosage is one drop in the affected eye(s) once daily in the evening.
In case of overdose, call your healthcare provider or local poison control center, or seek emergency medical attention right away.
- Keep this medication in the bottle it came in, tightly closed, and out of reach of children.
- Store unopened bottles in the refrigerator. Opened bottles can be stored at room temperature and away from excess heat and moisture (not in the bathroom).
- Dispose of the bottle 31 days after opening, even if there is some solution left in the bottle.