Qbrexza

Qbrexza is used to treat excessive sweating in adults and pediatric patients 9 years of age and older. Qbrexza is flammable; keep away from heat or flame.

Qbrexza Overview

Reviewed: July 5, 2018
Updated: 

Qbrexza is a prescription medication used to treat excessive sweating known as primary axillary hyperhidrosis in adults and pediatric patients 9 years of age and older.

The main active ingredient in Qbrexza, glycopyrronium, is a competitive inhibitor of acetylcholine receptors that are located on certain peripheral tissues, including sweat glands. This means Qbrexza blocks the “sweat signals” sent to certain sweat glands, inhibiting the action of acetylcholine on those glands and thereby reducing the extent of sweating.

This medication is a pre-moistened, medicated cloth towelette that comes in individually wrapped packets. Apply Qbrexza once a day to clean and dry underarms using 1 cloth every 24 hours. Throw away the cloth after use and wash hands right away.

Common side effects of Qbrexza include dry mouth, pupil dilation, and urinary hesitation. Qbrexza can also cause blurred vision. Do not drive or operate heavy machinery until you know how Qbrexza affects you.

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Qbrexza Cautionary Labels

precautions

Uses of Qbrexza

Qbrexza is a prescription medication used to treat excessive sweating known as primary axillary hyperhidrosis in adults and pediatric patients 9 years of age and older.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Glycopyrronium Bromide

For more information on this medication choose from the list of selections below.

Side Effects of Qbrexza

Serious side effects have been reported with Qbrexza. See the “Qbrexza Precautions” section.

Common side effects of Qbrexza include the following:

  • Dry mouth
  • Dilation of the pupils
  • Sore throat
  • Skin redness
  • Burning/stinging or itching in underarm area
  • Headache
  • Problems with urination
  • Blurred vision
  • Nasal, throat, eye and skin dryness
  • Constipation

This is not a complete list of Qbrexza side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Qbrexza Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • anticholinergics such as glycopyrrolate (Cuvposa, Robinul), trospium (Sanctura), oxybutynin (Anturol, Gelnique, Oxytrol, Ditropan), solifenacin (Vesicare), dicyclomine (Bentyl), propantheline (Pro-Banthine), and atropine (Atropen, Sal-Tropine)

This is not a complete list of Qbrexza drug interactions. Ask your doctor or pharmacist for more information.

Qbrexza Precautions

Serious side effects have been reported with Qbrexza including the following:

  • New or worsened urinary retention: People who use Qbrexza may develop new or worse urinary retention. Urinary retention can result from a blockage in your bladder or a larger than normal prostate. Stop using Qbrexza and call your healthcare provider right away if you experience any of the following symptoms: difficulty urinating; urinating frequently; urinating in a weak stream or drips; full bladder or difficulty emptying your bladder.
  • Problems with control of your body temperature: Qbrexza can cause you to have decreased sweating in areas other than the underarm leading to overheating and the development of heat illness when in hot or very warm temperatures. Stop using Qbrexza and call your healthcare provider right away if you experience any of the following symptoms: lack of sweating on your body; hot or red skin; decreased alertness or passing out; fast, weak pulse; fast, shallow breathing; increased body temperature.
  • Blurred Vision: Stop using Qbrexza and call your healthcare provider if you develop blurred vision. Do not drive, operate machinery, or do hazardous work until your vision is clear.

Do not use Qbrexza if you have certain medical conditions that can be made worse by taking an anticholinergic medicine such as glaucoma, severe ulcerative colitis or certain other serious bowel problems associated with severe ulcerative colitis, myasthenia gravis, and Sjogren’s syndrome.

Talk to your healthcare provider if you are not sure if you have a medical condition that can be made worse by taking an anticholinergic medicine.

Qbrexza may cause you to have blurred vision that is temporary. If you develop blurred vision, call your healthcare provider, stop using Qbrexza and do not drive, operate machinery, or do hazardous work until your vision is clear.

Qbrexza is flammable. Avoid heat and flame while applying Qbrexza to your skin.

Do not take Qbrexza if you are allergic to Qbrexza or to any of its ingredients.

Qbrexza Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Qbrexza, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before using Qbrexza, tell your healthcare provider about all of your medical conditions, including if you:

  • have prostate or bladder problems, or problems passing urine
  • have kidney problems
  • are pregnant or plan to become pregnant. It is not known if Qbrexza will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Qbrexza passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Qbrexza.

Tell your healthcare provider about all the medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.

Qbrexza and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-controlled studies that have been done in pregnant women. In animal studies, no adverse effects or incidence of defects were seen. Qbrexza should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

Qbrexza and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Qbrexza crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Qbrexza.

Qbrexza Usage

Use Qbrexza exactly as prescribed.

  • Use Qbrexza exactly as your healthcare provider tells you to use it.
  • Qbrexza comes as a single-use pre-moistened cloth in individual pouches.
  • Qbrexza should be applied to the clean, dry, intact skin, of your underarm areas only. Do not apply Qbrexza to broken skin. Do not cover the treated area with a plastic (occlusive) dressing.
  • Apply Qbrexza to both underarm areas using 1 cloth 1 time every 24 hours.

Applying Qbrexza:

  • Carefully tear open the pouch to avoid tearing the Qbrexza cloth.
  • Unfold the Qbrexza cloth and apply Qbrexza by wiping across 1 entire underarm 1 time. Using the same Qbrexza cloth,
  • wipe across the other underarm 1 time.
  • Throw away (discard) the used Qbrexza cloth in the trash.
  • Wash your hands right away after you apply Qbrexza and have thrown away the cloth. It is important that you wash your hands because the Qbrexza that is still on your hands can cause you to have blurred vision if you touch your eyes.
  • Do not reuse the Qbrexza cloth.

Qbrexza Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Recommended Dose: Apply Qbrexza to both underarm areas using 1 cloth 1 time every 24 hours.

Qbrexza Overdose

If you take too much Qbrexza, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Associated signs and symptoms related to excessive anticholinergic activity may include:

  • Flushing
  • Elevated body temperature
  • Abnormally rapid heart rate
  • GI blockage
  • Urinary retention
  • Loss of eye accommodation and light sensitivity due to pupil dilation

Other Requirements

  • Store Qbrexza at room temperature between 68°F and 77°F (20°C and 25°C).
  • Qbrexza is flammable. Keep Qbrexza away from heat and flame.

  • Keep Qbrexza and all medicines out of the reach of children.