Rocklatan

Rocklatan is a prescription medication used to treat open-angle glaucoma or high blood pressure of the eye. It is a single product containing 2 medications: netarsudil and latanoprost. Netarsudil, which belongs to a group of drugs called rho kinase inhibitors, works by increasing outflow from the eye. Latanoprost, which belongs to a group of drugs called prostaglandin analogs, also works to decrease pressure in the eye.

Rocklatan is an eye drop that is given once daily in the evening.

The most common side effect is redness around the eyes.

Rocklatan is a prescription medicine used to treat open-angle glaucoma or high blood pressure in the eyes.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Rocklatan. See the “Rocklatan Precautions” section.

Common side effects of Rocklatan include the following:

• Redness around eyes
• Eye color changes 
• Eyelash changes
• Brown or gray 'whorl'-shaped deposits in eye
• Reactivation of herpes infection
• Inflammation of eye and/or surrounding area
• Eye bleeding
• Eye Pain
• Bacterial eye infection

This is not a complete list of Rocklatan side effects.

Ask your doctor or pharmacist for more information. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take, including ones that you may only be taking for a short time, such as antibiotics.  Especially tell your doctor if you are taking:

• eye drops or contact lens solutions containing thiomersal
• prostaglandins or other prostaglandin analogs (bimatoprost, latanoprostene, tafluprost)

This is not a complete list of Rocklatan drug interactions.  Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Rocklatan including:  

• Macular edema, a buildup of in the eye, may occur. Tell your healthcare provider right away if you have some or all of the following symptoms of macular edema.
  • Blurry or wavy vision especially 
  • 'Washed out' color vision
  • Vision loss, especially in center of visual field
• Punctate keratitis is an eye disorder that may result in lost vision. Tell your healthcare provider right away if you have some or all of the following symptoms of punctate keratitis.
  • red eyes
  • watery eyes 
  • sensitivity to light
  • decreased vision 

Do not take Rocklatan if you are allergic to any of its ingredients.

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Rocklatan, there are no specific foods that you must exclude from your diet when receiving this medication.

Before you take Rocklatan tell your doctor about all your medical conditions. Especially tell your doctor if you:

• are allergic to Rocklatan or to any of its ingredients
• are pregnant or plan to become pregnant 
• are breastfeeding or plan to breastfeed
• have a history of inflammation of the eyes or area around eyes
• have active infection 
• have history of herpes infection

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Tell your doctor if you are pregnant or plan to become pregnant.

Studies on pregnant women have not be conducted for Rocklatan.  If administered correctly as drops into the eye, there is little absorption into the whole body system of the medications. In animal studies, pregnant animals were given Rocklatan, and some babies had problems. However, these animals were administered the medication directly into the vein (IV). 

Tell your doctor if you are breastfeeding or if you plan to breastfeed.

It is not known if Rocklatan crosses into human breast milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the bennefits outweigh the risk of using Rocklatan.

Take Rocklatan exactly as prescribed.

Rocklatan is an eye solution that is given as one drop once daily in affected eye(s). It is generally administered in the evening time. If it is given in addition to other types of eyedrops, it is recommended to seperate the medications by at least five minutes.

If you miss a dose of Rocklatan, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not take 2 doses of Rocklatan at the same time.

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

• the condition being treated

• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your weight
• your height
• your age
• your gender

The recommended dose of Rocklatan [netarsudil 0.02% and latanoprost 0.005% opthalmic solution] for the treatment of open-angle glaucoma or high blood pressure of the eyes is a single drop of solution applied directly to the eye once per day in the evening.

If you take too much Rocklatan call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

• Keep Rocklatan eye solution refrigerated at 2° to 8°C (36° to 46°F).
• Keep Rocklatan liquid in tightly sealed container, out of the light.
• Keep this and all medicines out of the reach of children.