Trelstar
Trelstar treats prostate cancer. During the first weeks of treatment, patients may experiencing worsening of symptoms such as bone pain or difficulty urinating.
Trelstar Overview
Trelstar is a prescription medication used to treat prostate cancer in men. Trelstar belongs to a group of drugs called gonadotropin releasing hormone (GnRH) agonists, which help slow the growth of prostate cancer cells by affecting testosterone production in the testes.
This medication comes in an injectable form to be given into the buttock by a healthcare provider, once every 4, 12, or 24 weeks.
Some of the common side effects of Trelstar include hot flashes, headache, and bone pain.
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Trelstar Cautionary Labels
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Uses of Trelstar
Trelstar is a prescription medicine approved for the treatment of the symptoms associated with advanced prostate cancer.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Manufacturer
Generic
Triptorelin
For more information on this medication choose from the list of selections below.
Trelstar Drug Class
Trelstar is part of the drug class:
Side Effects of Trelstar
After the first Trelstar injection, blood testosterone levels increase, which may cause a worsening of prostate cancer symptoms during the first few weeks of treatment. These symptoms may include:
- bone pain
- difficulty urinating
- spinal cord injury
- blood in urine
- urinary tract blockage
Tell your doctor if these symptoms do not go away after a few weeks or if they become severe.
In clinical trials, common side effects of Trelstar included:
- hot flashes
- headache
- bone pain
- impotence
- pain at injection site
- difficulty falling asleep or staying asleep
- leg or joint pain
Less common, more serious side effects can occur. Tell your doctor right away if you experience any of these symptoms:
- hives
- rash
- itching
- difficulty breathing or swallowing
- hoarseness
- chest pain
- pain in the arms, back, neck, or jaw
- slow or difficult speech
- dizziness or fainting
- weakness or numbness of an arm or leg
- not able to move legs
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles or legs
- bone pain
- painful or difficult urination
- blood in urine
- frequent urination
- extreme thirst
- weakness
- blurred vision
- dry mouth
- nausea
- vomiting
- breath that smells fruity
- decreased consciousness
This is not a complete list of Trelstar side effects. Ask your doctor or pharmacist for more information.
Trelstar Interactions
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- medications for depression or mental illness; methyldopa (in Aldoril); metoclopramide (Reglan); or reserpine.
This is not a complete list of Trelstar drug interactions. Ask your doctor or pharmacist for more information.
Trelstar Precautions
Do not receive Trelstar injections if you are allergic to Trelstar or any of the other ingredients in Trelstar injections.
Serious allergic reactions to Trelstar have occurred. Tell your doctor right away if you experience signs of an allergic reaction including:
- an unexplained rash
- hives
- itching
- difficulty breathing or swallowing
During the first few weeks of Trelstar treatment, testosterone levels may increase, causing some patients experience a worsening of prostate cancer symptoms or new symptoms including:
- bone pain
- numbness or tingling
- loss of movement of part of the body
- blood in urine
- urinary tract blockage
If, after 3 or 4 weeks these symptoms do not go away, or if they become severe, notify your doctor.
With Trelstar use there is an increased risk of developing diabetes, high blood pressure, heart attack, stroke, sudden cardiac death. Talk to your doctor about the risks and benefits of Trelstar therapy.
Trelstar Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Trelstar there are no specific foods that you must exclude from your diet when receiving Trelstar.
Inform MD
Before receiving Trelstar, tell your doctor about all of your medical conditions including if you:
- are allergic to Trelstar or any other medicine. Especially tell your doctor if you are allergic to drugs that are similar to Trelstar such as goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Lupron, Viadur, Eligard), and nafarelin (Synarel).
- have heart, kidney, or liver disease
- have diabetes, cancer that has spread to the spine or urinary tract, or difficulty urinating
- are pregnant or breastfeeding
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Trelstar and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
This medication falls into category X. This medicine is not approved for any use in women, although, sometimes it is prescribed for "off-label", or unapproved uses. Trelstar should not be used in women who are pregnant. Trelstar decreases production of estrogen in women, which can cause miscarriage if taken by a pregnant woman.
Before receiving Trelstar, tell your doctor if you are pregnant or plan to become pregnant. Tell your doctor right away if you become pregnant while receiving Trelstar.
Trelstar and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Trelstar is excreted in human breastmilk or if it will harm your nursing baby.
Trelstar Usage
Trelstar comes as a powder to be mixed with sterile water. It is given by a single injection into the buttock by a healthcare provider, in a medical facility such as a hospital, clinic, or doctor's office.
Trelstar can be given every 4, 12, or 24 weeks, depending on the dosage form your doctor prescribes. An injection of Trelstar 3.75 mg is usually given every 4 weeks. An injection of Trelstar 11.25 mg is usually given every 12 weeks. An injection of Trelstar 22.5 mg is usually given every 24 weeks.
Trelstar may cause an increase in certain hormones in the first few weeks after injection. Your doctor will monitor you carefully for any new or worsening symptoms during this time.
If you miss a dose, be sure to make a follow up appointment.
Trelstar Dosage
Take this medication exactly as prescribed by your doctor.
Trelstar can be given every 4, 12, or 24 weeks, depending on the dosage form your doctor prescribes.
The recommended dose of Trelstar is 3.75 mg every 4 weeks, 11.25 mg is every 12 weeks, and 22.5 mg given every 24 weeks.
Trelstar Overdose
If Trelstar is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.