Diabetes is a big problem in the US — and thus, it is a big focus of doctors, researchers and pharmaceutical companies alike. New medications and developments alter how diabetes is treated.

Call it a gut reaction. A popular diabetes medication works by helping gastrointestinal hormones that encourage insulin production. The same medication may also help ward off autoimmune diseases.

Saxagliptin helps diabetes patients control blood sugar levels. While it may not raise heart attack risk, the medication may have a negative effect on heart failure patients.