Triptodur

Triptodur treats central precocious puberty in pediatric patients 2 years and older. Patients should not miss or delay the scheduled dose of one injection every 24 weeks.

Triptodur Overview

Reviewed: June 19, 2018
Updated: 

Triptodur is a prescription medication used to treat pediatric patients 2 years of age and older with central precocious puberty (CPP).

Triptodur belongs to a group of drugs called gonadotropin releasing hormone (GnRH) agonists, which help regulate sex hormone levels.

This medication comes in suspension form that can be injected into the muscle by a healthcare professional.

Common side effects of Triptodur include injection site reactions, menstrual bleeding, and hot flush.

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Triptodur Cautionary Labels

precautionsprecautions

Uses of Triptodur

Triptodur is a prescription medication used to treat central precocious puberty in patients 2 years of age and older.

Triptodur has not been studied in children with renal or hepatic impairment.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Triptodur Drug Class

Triptodur is part of the drug class:

Side Effects of Triptodur

Serious side effects have been reported with Triptodur. See the “Triptodur Precautions” section.

Common side effects of Triptodur include the following:

  • Injection site reactions (pain, redness, pruritus, swelling)
  • Hot flush
  • Headache
  • Vaginal bleeding

This is not a complete list of Triptodur side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Triptodur Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • Medications that treat high prolactin levels such as bromocriptine (Cycloset).

This is not a complete list of Triptodur drug interactions. Ask your doctor or pharmacist for more information.

Triptodur Precautions

Serious side effects have been reported with Triptodur including the following:

  • Psychiatric events. Tell your healthcare provider right away if you have some or all of the following symptoms of psychiatric events.
    • Crying
    • Irritability
    • Impatience
    • Anger
    • Aggression
  • Convulsions. These sudden acts of involuntary contractions of muscles occured in patients with a history of seizures, brain or spinal chord problems, and patients on antidepressants that have been associated with convulsions such as bupropion and fluoxetine.

  • Hypersensitivity reactions. Immediately seek medical attention if any reaction occurs.

    • Anaphylactic shock
    • Hypersensitivity
    • Angioedema

Do not take Triptodur if you:

  • are allergic to Triptodur or to any of its ingredients.

Triptodur Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Triptodur, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Triptodur, tell your doctor about all of your child’s medical conditions. Especially tell your doctor if your child:

  • has a history of mental problems
  • has a history of seizures
  • has a history of brain or brain vessel problems or tumors
  • is breastfeeding or plans to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Triptodur and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. Based on mechanism of action in humans and findings of increased pregnancy loss in animal studies, Triptodur may cause fetal harm when given to pregnant women. Therefore, it is contraindicated in women who are pregnant.

Triptodur and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Triptodur crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Triptodur.

Triptodur Usage

Receive this medication as directed by your doctor.

Triptodur comes in powder form and is later reconstituted into an injectable form that is given into the muscle by a healthcare professional once every 24 weeks.  

It is important to adhere to the Triptodur dosing schedule of one injection every 24 weeks. Patients should not miss or delay a scheduled dose.

Triptodur should be discontinued at the appropriate age of onset of puberty at the discretion of the physician.

Triptodur Dosage

Take this medication exactly as prescribed by your doctor.

The recommended dose of Triptodur for the treatment of central precocious puberty is 22.5 mg reconstituted with 2 mL of sterile water, and injected into the muscle by a healthcare professional once every 24 weeks.

Triptodur Overdose

If Triptodur is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

Store at 20-25°C (68-77°F).

Do not freeze.